Dr. Khakhu Mathivha

Khakhu Mathivha is a South African clinical researcher whose work centers on pediatric infectious diseases and genomic medicine in resource-limited settings. Affiliated with academic and public health institutions in Johannesburg, Mathivha contributes to advancing child health through translational research that bridges clinical care and emerging diagnostic technologies.

Recent research highlights the implementation of clinical exome sequencing in hospitalized South African infants, demonstrating its value for diagnosing genetic disorders in under-represented African populations. This work addresses critical gaps in genomic data diversity, workforce capacity, and context-appropriate diagnostic strategies, supporting the integration of precision medicine into state healthcare systems.

Earlier studies examined infants exposed to maternal tuberculosis and HIV, evaluating outcomes following chemoprophylaxis and describing perinatal risk factors. Together, these publications reflect a focus on improving early diagnosis and management of vulnerable infants. The analysis is based on a limited set of available publications at present.