Dr. Thandiswa Ngcungcu

Thandiswa Ngcungcu is a biomedical researcher whose work centers on molecular genetics and translational approaches to dermatological and ocular disease. Her research has contributed to clarifying the genetic and regulatory mechanisms underlying keratolytic winter erythema, particularly the role of enhancer duplications driving CTSB overexpression in affected families.

Her publications demonstrate strong expertise in functional genomics, gene regulation, and skin biology, integrating sequencing technologies, expression analysis, and histopathology to link non-coding genomic variation with disease phenotype. This work has advanced understanding of enhancer-mediated gene dysregulation in inherited skin disorders.

More recent research expands into ocular surface biology, establishing non-invasive conjunctival cell sampling for whole-transcriptome sequencing. This methodological contribution supports accessible molecular profiling of eye disease. The analysis is based on limited available publications at the moment, yet reflects a focused and evolving translational research trajectory.