Human Genetics

Division of Human Genetics, University of the Witwatersrand is based in Johannesburg, South Africa. Part of a public research university established in 1922, the division is a leading academic and clinical genetics center in Africa, integrating diagnostics, teaching, and translational research to address inherited and complex diseases in diverse populations.

Research spans hereditary cancer genetics, rare Mendelian disorders, neurogenetics, psychiatric epigenetics, and congenital conditions. Strong emphasis is placed on African genomic diversity, with notable contributions in BRCA-associated breast cancer, STAC3 myopathy, albinism, anterior segment eye disorders, and chromosomal syndromes, advancing molecular diagnosis and population-specific variant discovery.

The division also leads work in genomic data governance, biomarker development, and environmental health, including heat-related maternal outcomes. Its role in African-led genomics initiatives and ethical data access frameworks positions it as a key driver of equitable, responsible genomics research and capacity building across the continent.