Dr. Elyzka Badenhorst

Elyzka Badenhorst is a clinical researcher in neuromuscular medicine and anesthetic-related muscle disorders, known for contributions to the understanding of malignant hyperthermia and inherited myopathies. Published work in leading journals reflects sustained engagement with muscle pathology, diagnostic testing, and the molecular mechanisms underlying abnormal calcium regulation in skeletal muscle.

Research has extensively examined the caffeine–halothane contracture test, highlighting its diagnostic reliability while addressing rare false-negative outcomes. Investigations into FKBP12, ryanodine receptor function, and pharmacologic triggers such as FK506 and rapamycin advanced insight into calcium dysregulation and susceptibility to malignant hyperthermia. Additional studies explored heat shock protein expression and genetic patterns in syndromic and familial cases.

Broader contributions encompass distal and centronuclear myopathies, Duchenne muscular dystrophy in female carriers, metabolic muscle disease, and distinctive histopathological features including internalised capillaries and mitochondrial abnormalities. This body of work demonstrates expertise in clinicopathological correlation, muscle biopsy interpretation, and the interface between neurology, genetics, and anesthesiology.