Dr. Khanyisile Kgoadi

Khanyisile Kgoadi is a biomedical researcher whose work centers on host–pathogen interactions in infectious diseases, with a particular focus on HIV and tuberculosis. Her research integrates immunology, cellular biology, and metabolic profiling to better understand how immune dysfunction contributes to disease susceptibility and progression in co-infected populations.

Her publications highlight key themes such as impaired immune signaling in HIV-positive individuals and the role of immune cell subsets in tuberculosis pathogenesis. Notably, her work on alveolar macrophage responses and TNF signaling provides insight into why individuals with HIV remain vulnerable to tuberculosis despite therapy. Additional studies explore innovative approaches, including nanoparticle-based targeting of suppressor cells and metabolomic analyses of HIV-associated immune alterations.

Based on a limited set of available publications, Kgoadi’s research demonstrates strength in applying advanced techniques such as single-cell analysis and metabolomics to complex infectious disease questions. Her contributions support a deeper understanding of immune dysregulation and may inform future therapeutic and diagnostic strategies in HIV–TB co-infection.