Molecular Medicine and Haematology

Molecular Medicine and Haematology is an academic research unit based in Johannesburg, South Africa, operating within a university affiliated and public health laboratory environment. Established in the mid 1990s, it functions as a multidisciplinary biomedical research entity focused on translational medicine, laboratory science, and clinical haematology.

Its research centers on hemophilia, coagulation disorders, gene therapy, and diagnostic hematopathology. Publications highlight leadership in advancing AAV and lentiviral gene therapies, optimizing management of transaminitis after factor VIII gene transfer, and refining recombinant factor VIIa use. Strong emphasis is placed on standardization, quality assurance, and equitable access to advanced therapies.

Additional strengths include lymphoma diagnostics in HIV prevalent settings, pulmonary ultrasound in critical care, and molecular microbiology. The work demonstrates integration of clinical insight with laboratory innovation, contributing to safer gene therapy implementation, improved bleeding management, and cost effective diagnostics in resource constrained environments.