Endocrinology

Endocrinology at Charlotte Maxeke Johannesburg Academic Hospital in Johannesburg, South Africa, is a tertiary academic clinical unit within a major public teaching hospital affiliated with the University of the Witwatersrand. Established as part of the hospital’s specialist services in the late twentieth century, it delivers advanced endocrine care while supporting training and research in internal medicine and subspecialties.

Research centers on dyslipidemia, cardiovascular risk reduction, diabetes management, and complex endocrine disorders. Work on PCSK9 inhibition, novel lipid lowering therapies, and access to emerging treatments highlights leadership in preventive cardiometabolic care. Studies on pancreatic beta cell replacement and transplant strategies address unmet needs in insulin deficient diabetes.

Case reports and clinical investigations in pituitary disease, tumor induced hypoglycemia, electrolyte disorders, and COVID-19 risk stratification reflect strong diagnostic expertise and real world relevance. Validation of point of care lipid testing demonstrates commitment to accessible care. The unit advances endocrine practice in resource constrained settings while shaping policy and clinical standards.