Dr. Pumza Magangane

Pumza Magangane is a South African researcher in pathology and molecular oncology, affiliated with Charlotte Maxeke Johannesburg Academic Hospital and the University of the Witwatersrand. Her work centers on cancer biology in African populations, with a strong focus on translational pathology and biomarker discovery in resource-constrained settings.

Her research explores microsatellite instability, Lynch syndrome, colorectal cancer disparities, and the immune microenvironment in breast cancer. She has examined tumour-infiltrating lymphocytes, molecular subtypes, and risk factor heterogeneity in Kenyan and South African cohorts, contributing to a more inclusive understanding of cancer etiology and prognosis.

Magangane also investigates lymphoma pathology, MYC expression in Burkitt lymphoma, microRNA signatures linked to invasion and chemoresistance, and epigenetic regulation in TB-HIV co-infection. Her scholarship integrates molecular techniques with clinicopathological analysis, advancing precision oncology and context-relevant diagnostic strategies in Africa.