Staff

Prof William Daniels

Head of School: Physiology william.daniels@wits.ac.za

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William Daniels is a neuroscientist whose work centers on neuropsychopharmacology, addiction biology, and mental health in African contexts. His research integrates molecular, cellular, and behavioral approaches to understand how substances such as heroin, cocaine, and emerging street drugs influence brain function, neuroinflammation, and gene regulation. He has also contributed to advancing African neuroscience through collaborative and strategic initiatives.

Recent publications highlight investigations into epigenetic modulation of the OPRM1 gene in heroin users, cytotoxic effects of nyaope on neuronal cells, and the therapeutic potential of CB2 receptor agonists in cocaine-related behaviors. His scholarship further explores ketamine as a treatment for depression in resource-limited settings and examines suicidality among individuals with substance use disorders.

Daniels’ broader contributions span neurovirology, neuroplasticity under antiretroviral therapy, neuroepigenetics, and innovative interventions such as immersive virtual reality to address racial prejudice. This interdisciplinary portfolio underscores a commitment to translational neuroscience, public mental health, and contextually relevant biomedical research in Africa.

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