Dr. Mpho Maphayi

Mpho Maphayi is a South African medical researcher whose work is closely associated with the National Health Laboratory Service and Charlotte Maxeke Johannesburg Academic Hospital. Her scholarship centres on clinical chemistry, laboratory medicine, and infectious diseases, with a strong focus on improving diagnostic accuracy and laboratory practice in resource-constrained settings.

Her publications explore pre-analytical stability of hormones such as C-peptide and insulin, optimisation of vitamin D testing, and data-driven evaluations of prostate-specific antigen use in urban populations. She has also contributed to validation studies of SARS-CoV-2 immunoassays and large seroprevalence investigations, strengthening local evidence for COVID-19 surveillance and diagnostic performance.

Across her body of work, Maphayi demonstrates expertise in laboratory data mining, assay validation, and translational clinical research. Her contributions support evidence-based testing guidelines, highlight disparities in disease burden, and advance quality assurance in diagnostic services within the South African public health sector.