Staff

Dr. Tumane Mafojane

Lecturer Oral Medicine and Periodontology tumane.mafojane@wits.ac.za

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Tumane Mafojane is a researcher in oral biology and microbiology, with a focus on fungal pathogens affecting the oral cavity. Scholarly work centers on Candida albicans and its role in oral candidiasis, particularly among vulnerable populations such as denture wearers and individuals living with HIV. Research published in Archives of Oral Biology highlights expertise in antifungal therapeutics and microbial virulence mechanisms.

The featured study investigates how subinhibitory concentrations of gentian violet influence germ tube formation and epithelial adherence, two key virulence factors of C. albicans. Findings demonstrate that beyond fungicidal action, gentian violet can significantly impair pathogenicity, offering insight into sustained therapeutic effects in clinical settings.

Based on the limited publications currently available, the research profile emphasizes experimental microbiology, antifungal susceptibility testing, and translational relevance to oral health care. The work contributes to a deeper understanding of alternative antifungal strategies and their potential benefits in managing candidiasis.

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