Staff

Dr. Siyabonga Khoza

Head of Department Chemical Pathology siyabonga.khoza@wits.ac.za

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Siyabonga Khoza is a South African laboratory medicine researcher whose work bridges clinical biochemistry, proteomics, and public health. Affiliated with academic and public laboratory institutions in South Africa, his research focuses on improving diagnostic accuracy and strengthening health systems in resource-constrained settings, with particular attention to chronic kidney disease, diabetes, and HIV-associated comorbidities.

His proteomic studies explore urinary biomarkers across stages of kidney dysfunction and albuminuria in African populations, highlighting molecular pathways linked to haemostasis, immunity, and growth factor regulation. This work advances early detection strategies for kidney disease and addresses gaps in evidence from underrepresented groups, contributing to precision diagnostics in nephrology.

Complementing biomarker discovery, his health services research leverages national laboratory databases to examine diabetes care cascades, guideline adherence, and integration of HIV and noncommunicable disease services. Additional contributions in laboratory quality management and pre-analytical stability studies demonstrate a strong commitment to improving diagnostic reliability and translating laboratory insights into better population health outcomes.

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