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Kristie Bloom is a South African researcher specializing in gene therapy, synthetic mRNA technologies, and vaccine innovation, with strong ties to hepatitis B virus research and translational immunology. Her work is closely associated with efforts to advance molecular medicine and vaccine manufacturing capacity within Africa, contributing to regional scientific leadership in genetic therapeutics.
Her publications highlight expertise in self-amplifying RNA platforms, lipid nanoparticle delivery systems, and non-viral vectors for infectious diseases. Bloom has contributed influential reviews and experimental studies on mRNA vaccines, CRISPR-based strategies, and hepatotropic gene therapies, particularly targeting chronic HBV infection and HBV-related liver cancer. This body of work reflects a focus on safe, scalable, and accessible genetic interventions.
A recurring theme in her scholarship is addressing vaccine inequity and strengthening pandemic preparedness through adaptable RNA platforms. By bridging gene therapy and next-generation vaccine technologies, Bloom has helped shape discourse on dose-sparing vaccines, local manufacturing, and innovative therapeutics tailored to resource-constrained settings.
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Most recent scholarly works and contributions.