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Mhairi Maskew is a public health researcher specializing in HIV epidemiology, health systems research, and antiretroviral therapy outcomes in Southern Africa. Affiliated with the University of the Witwatersrand and the Empilweni Services and Research Unit in Johannesburg, her work is closely linked to large clinical cohorts such as Themba Lethu and Rahima Moosa Mother and Child Hospital, strengthening evidence from routine care settings.
Her research focuses on retention in HIV care, early treatment disengagement, and differentiated service delivery models. Through cohort analyses, implementation studies, and mixed-methods research such as the PREFER study, she examines patient preferences, engagement patterns, and service innovations aimed at improving outcomes during the critical first months of treatment.
Maskew has also advanced the application of machine learning to predict treatment interruption and inform targeted interventions. Additional contributions include evaluating regimen transitions, including shifts to dolutegravir, and assessing associated clinical outcomes. Her work bridges rigorous analytics with policy-relevant insights, influencing HIV treatment strategies across South Africa and the broader region.
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