Dr. Ayesha Khan

Ayesha Khan is a South African critical care researcher affiliated with Chris Hani Baragwanath Academic Hospital, with a strong focus on intensive care medicine in resource-constrained settings. Her work spans adult and pediatric critical care, addressing pressing clinical challenges in sepsis, toxicology, and respiratory failure within multidisciplinary ICUs.

Her research prominently examines optimization of antibiotic strategies in sepsis, including prolonged versus intermittent β-lactam infusions. Contributions to a major systematic review and meta-analysis published in JAMA, alongside a randomized controlled trial in a South African ICU, highlight expertise in evidence synthesis and clinical trial methodology, informing standards of care in severe infections.

Dr. Khan has also investigated poisoning-related critical illness, hemoadsorption in drug overdose, pediatric acute respiratory distress syndrome, and quality-of-care practices such as tracheal cuff pressure monitoring. Collectively, her publications demonstrate a commitment to improving outcomes through context-specific data, pragmatic study designs, and translational insights for critical care systems in Africa.