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Ian Sanne is a South African clinician-researcher internationally recognized for leadership in HIV and tuberculosis clinical research. Based at the University of the Witwatersrand and associated with leading clinical research units in Johannesburg, his work has shaped treatment strategies and public health responses across sub-Saharan Africa.
Recent publications highlight a strong focus on innovative tuberculosis regimens, including rifapentine-based shortening strategies and first-in-class agents such as BTZ-043. His research also explores microbiome effects of TB therapy and advances capacity building through the PanACEA network, strengthening sustainable clinical trial infrastructure in Africa.
Sanne has played a central role in large-scale COVID-19 vaccine effectiveness and safety studies, notably the Sisonke programme, and in analyses of COVID-19 outcomes among people living with HIV. Across HIV, TB, and emerging infections, his work integrates rigorous clinical trials with real-world surveillance to inform policy and improve care in high-burden settings.
Latest publications
Most recent scholarly works and contributions.