Dr. Marc Hauptfleisch

Marc Hauptfleisch is a South African clinician-researcher in paediatric neurology with strong ties to academic hospitals serving diverse populations. His work centres on genetic and acquired neurological disorders in children, with particular attention to conditions affecting underrepresented African populations. Through hospital-based and collaborative research, he contributes to improving diagnostic pathways and genetic counselling in resource-constrained settings.

Research highlights include influential studies on STAC3-related congenital myopathy in Southern Africa, helping to clarify its clinical spectrum and ancestral origins. Additional work on spinal muscular atrophy in black South African children has expanded understanding of genetic patterns and phenotypic presentation in sub-Saharan Africa, addressing important gaps in global neuromuscular literature.

Hauptfleisch has also published on paediatric neuroinflammatory and metabolic conditions, drug-related neurological effects, and bone health in chronically ill children. Case reports and reviews on encephalopathy, movement disorders, and antiretroviral toxicity demonstrate clinical acumen and a focus on practical diagnostic awareness. Collectively, his scholarship strengthens paediatric neurological care across the region.