Aspro Ismail Kalla

Ismail Kalla is a South African clinician-researcher in pulmonary and critical care medicine, with strong affiliations to tertiary academic hospitals in Johannesburg. His scholarship centers on respiratory disease in high HIV and tuberculosis settings, integrating infectious diseases with intensive care and emergency medicine. He has contributed to leading international journals and multinational collaborations, reflecting sustained engagement in globally relevant respiratory research.

His work highlights critical illness in people living with HIV, post-tuberculosis lung sequelae, pulmonary vascular disease, and bronchiectasis, including contributions to national position statements. He has advanced understanding of post-COVID-19 lung impairment in African populations and evaluated risk stratification tools for COVID-19, venous thromboembolism, and shock in resource-constrained environments.

Kalla has also participated in major therapeutic trials, including large international studies on remdesivir and tezepelumab, underscoring expertise in clinical trial methodology and translational therapeutics. Across his publications, a consistent focus emerges on adapting global evidence to local disease burdens, strengthening critical care pathways, and improving outcomes in settings heavily affected by HIV and tuberculosis.