Aspro Lee Fairlie

Lee Fairlie is a South African clinician-researcher recognized for leadership in pediatric infectious diseases, with a strong focus on tuberculosis, HIV, and maternal–child health. Affiliated with major academic and clinical research networks in South Africa, Fairlie has played a central role in advancing evidence-based care for children and pregnant women affected by complex infectious diseases, particularly in high-burden settings.

The publication record reflects expertise in multidrug-resistant and rifampicin-resistant tuberculosis, including preventive therapy, pharmacokinetics during pregnancy, and treatment optimization in children. Contributions to large clinical trials and individual participant data meta-analyses have informed global policy on the use of levofloxacin and novel regimens, as well as strategies to improve outcomes in vulnerable pediatric populations.

Research also spans HIV therapeutics, maternal antiretroviral exposure, vaccine implementation, and emerging infections such as Lassa fever and COVID-19. Work on long-acting HIV treatments, adolescent vaccine safety, and infant outcomes following maternal therapy highlights a commitment to translational research that bridges clinical trials, community perspectives, and public health impact.