Aspro Lesley Scott

Lesley Scott is a South African medical scientist and diagnostic researcher whose work has significantly advanced molecular testing for tuberculosis, HIV, and emerging respiratory infections. Affiliated with leading academic and public health institutions in South Africa, her research bridges laboratory science and health systems, supporting evidence-based implementation of diagnostics in high-burden settings.

Her publications demonstrate a strong focus on evaluating and optimizing molecular assays such as Xpert and cobas platforms for detection of Mycobacterium tuberculosis and drug resistance. She has contributed to studies on reflex testing strategies, non-sputum specimens, TB recurrence, migration-related transmission, and integrated TB–COVID testing, highlighting expertise in diagnostic accuracy, operational feasibility, and antimicrobial resistance surveillance.

Scott has also examined the broader health and economic impact of national molecular diagnostic programs, underscoring the value of diagnostics in public health investment. Collectively, her work strengthens laboratory networks, informs policy, and improves timely access to life-saving testing across diverse and resource-constrained environments.