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Andre Mochan is a South African neurologist based at the University of the Witwatersrand and Chris Hani Baragwanath Academic Hospital in Johannesburg. His work centers on neurological disorders in resource-limited and high HIV-prevalence settings, with a strong emphasis on conditions affecting underserved African populations. He has contributed to both clinical neurology and historical scholarship, highlighting South Africa’s role in the development of neuroimaging.
His research spans neuro-HIV, inflammatory neuropathies, myelopathies, optic neuritis, and toxic and metabolic encephalopathies. Notable contributions include influential studies on efavirenz-induced neurotoxicity, HIV-associated CIDP, and the spectrum of non-traumatic myelopathy in an endemic HIV context. Recent work addresses motor neuron disease in Black African patients and atypical mercury toxicity in artisanal miners, reflecting sustained engagement with locally relevant neurological challenges.
Mochan has also participated in collaborative genomic research on Parkinson’s disease in African and African admixed populations, helping to advance ancestry-specific insights into disease mechanisms. Across his publications, a consistent strength lies in integrating careful clinical observation with public health awareness, advocating for equitable representation of African populations in neurological research and improved context-sensitive care.
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