Ms. Therese Dix-Peek

Therese Dix-Peek is a South African biomedical researcher whose work spans molecular oncology, cancer genomics, and kidney disease in African populations. Affiliated with leading academic and clinical research institutions in South Africa, her research integrates genomic, epigenetic, and transcriptomic approaches to address diseases with high regional burden, particularly breast cancer, colorectal cancer, and HIV-associated kidney disorders.

Her oncology research focuses on molecular subtyping, gene expression profiling, and epigenetic regulation. Studies on PAM50 intrinsic subtypes and immunohistochemistry discordance have informed breast cancer classification in resource-limited settings. Investigations into FGFR2 variants and splice isoforms, as well as genome-wide 5-hydroxymethylcytosine dynamics in colorectal cancer metastasis, highlight expertise in functional genomics and biomarker discovery, with attention to population-specific genetic diversity.

In nephrology and infectious disease genomics, her work examines APOL1 risk variants, pharmacogenetic predictors of tenofovir-induced kidney toxicity, and clinical determinants of chronic kidney disease among African patients. Additional studies on microRNA expression in sarcoidosis and host–pathogen interactions demonstrate breadth in translational molecular research, emphasizing precision medicine and improved risk stratification in underrepresented populations.