Staff

Dr. Monare Thulo

Researcher Vaccines and Infectious Disease Analytics monare.thulo2@wits.ac.za

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Monare Thulo is a molecular biophysicist whose research centers on the structural and thermodynamic characterization of proteins involved in gene regulation and parasitic disease. Published work highlights detailed investigations of FOXP transcription factors, particularly FOXP2, elucidating how the forkhead and leucine zipper domains coordinate DNA binding, oligomerization, and regulatory dynamics central to speech and language biology.

Complementary studies examine glutathione transferases from Schistosoma japonicum, clarifying the molecular basis of enzyme inhibition by small molecules such as ellagic acid and bromosulfophthalein. Through crystallography, spectroscopy, and calorimetry, this research defines binding mechanisms and stability features that inform antiparasitic drug development strategies.

Across a focused body of publications, reflecting currently limited available works, Thulo demonstrates expertise in protein structure–function relationships, biophysical analysis, and ligand interaction profiling. The contributions advance understanding of transcriptional regulation and therapeutic targeting in infectious disease.

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