Dr. Sheefa Mirza

Sheefa Mirza is a cancer researcher whose work centers on tumor microenvironment biology, liquid biopsy, and RNA-based therapeutics. Her scholarship highlights the role of exosomes, long non-coding RNAs, and circulating biomarkers in cancer progression and precision oncology. She has contributed extensively to advancing non-invasive diagnostic strategies and translational approaches in colorectal, lung cancer, and mesothelioma research.

A major focus of her publications is exosome-mediated communication, including lncRNAs and siRNA delivery systems as emerging therapeutic platforms. She has explored immune modulation within the tumor microenvironment, particularly the interaction between cancer-associated fibroblasts and dendritic cells, and the regulatory role of microRNAs. Her reviews on AXL signaling and liquid biopsy underscore expertise in targeted therapy and resistance mechanisms.

Her research also spans experimental therapeutics, including graphene oxide–metal oxide composites and novel small-molecule anticancer agents validated through in vitro and in silico approaches. Studies on circulating cancer-associated fibroblasts and distinct colorectal cancer features in African populations reflect a commitment to clinically relevant biomarkers and population-specific oncology insights.