Aspro Sooraj Baijnath

Sooraj Baijnath is a biomedical researcher whose work spans cardiovascular, neurobiological, and inflammatory disease models, with strong expertise in mass spectrometry imaging and experimental pharmacology. His scholarship integrates molecular, physiological, and imaging approaches to interrogate mechanisms underlying hypertension, preeclampsia, cardiac dysfunction, and neuroinflammation, often using well-characterized rodent models.

A central theme of his research is the mechanistic dissection of inflammatory and neuroendocrine pathways, including NLRP3 inflammasome activation, HPA axis dysregulation, and cytokine-driven brain changes. His studies on ACTH-induced dysfunction, collagen-induced arthritis, and LPS-mediated cardiac injury highlight sex-specific effects, neurotrophic signaling, and pyroptotic pathways. Parallel work on ketamine and depression reflects an interest in translational neuropsychopharmacology within an African health context.

Baijnath also contributes methodological innovation, notably advancing MALDI-MSI protocols for multiomics tissue analysis and applying imaging tools to track drug distribution and metabolic alterations. Complementary investigations into phytocompounds such as quercetin and hesperidin, as well as toxicological assessments of heavy metals, demonstrate a broad yet coherent focus on disease mechanisms, therapeutic modulation, and biomarker discovery.